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Chen Shaodong

School of Traditional Chinese Medicine

Chen Shaodong.png

Biography

Prof. Chen Shaodong holds a Ph.D. in Combined TCM and Western Medicine Clinics from Shanghai University of Traditional Chinese Medicine (2008). As an accomplished scholar and experienced practitioner, he currently serves as the Dean of the School of Traditional Chinese Medicine at Xiamen University Malaysia. Dr. Chen is recognized as National Youth Qihuang Scholar and Outstanding Traditional Chinese Medicine Talents in China.

Dr. Chen actively engages in clinical practice at Xiamen University’s Xiang’an Hospital and the Beijing University of Chinese Medicine Xiamen Hospital. His research focuses on the integration of TCM and Western medicine, where he leads over 20 national and provincial research projects, publishes widely with over 70 scholarly articles, and has authored more than 10 books. For his contributions, he has received multiple awards, including two Third Prizes for Science and Technology Progress in Fujian Province, two Second Prizes for Scientific and Technological Progress in Xiamen, and two Second Prizes from the Chinese Association of Integrative Medicine.

Educational Background

  • 2008: PhD, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

  • 2003: Master of Pediatrics of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian Province, China.

  • 2000: Bachelor of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian Province, China.

Projects

  • Current

    • Integrative Approaches in TCM and Western Medicine for Chronic Diseases

    • Diagnostic Techniques and Tongue Imaging in Traditional Chinese Medicine

    • Clinical Application of TCM in the Treatment of Liver and Pulmonary Diseases

  • Past

    • Fujian Provincial Health Commission University Innovation Project, wzln201309, Study on the mechanism of RAAS expression regulation in hypertensive rats by the multi-target pathway of Wuling San, which strengthens the spleen - stimulates water - warms the Yang, and opens the pulse, 2014.1.1 - 2015.12.30, RMB 20,000, completed, project chairperson.

    • Project of Xiamen Science and Technology Bureau, 3502Z20134052, Development and Research of Chai Ling Anti-Hypertensive Punch, 2013.6.1 - 2015.5.30, RMB 150,000, completed, project chairperson.

    • Ministry of Science and Technology - National Key R&D Program - Research on Modernization of Chinese Medicine, 2017YFC1703303, “Research and Application of Artificial Intelligence Technology Based on Clinical Database of Tongue Diagnosis”, 2018.1.1 - 2021.12.31, RMB 2.6 million, ranked 7th.

    • National Natural Science Foundation of China (NSFC), 81673660, “Study on the mechanism of chlorogenic acid-gardenia glucoside combination regulating the polarization of nonalcoholic steatohepatitis based on the intestine-hepatic axis”, 2017.1.1 - 2020.12.31, RMB 570,000, ranked 3rd.

Selected Publications

  • Penghua Lai#, Linlin Zhang#, Yan Qiu, Jie Ren, Xue Sun, Ting Zhang, Liuyi Wang, Sijie Cheng, Sijia Liu, Hongli Zhuang, Daiwei Lu, Shaoliang Zhang, Huiqing Liang*, Shaodong Chen*. Heat stress reduces brown adipose tissue activity by exacerbating mitochondrial damage in type 2 diabetic mice. Journal of Thermal Biology. 2024,119: 103799.

  • Hui Wang#, Zhonghao Li, Qisheng Wang, Weixin Lin, Ziting Zhou, Xinru Mu, Yongwei Jiang, Shengfeng Lu, Shaodong Chen*, Zhigang Lu*. Gypenosides ameliorate morphine-induced immunosuppression with an increased proportion of thymic T lymphocyte subsets and are involved in the regulation of the cAMP-CREM/CREB-IL-2 pathway. Genes & Diseases. 2024, 11(3): 101049.

  • Zhou Z#, Lai P, Zhang S, Wang Y, Qu N, Lu D, Gao L, Xu L, Yang Y, Zhang T, Sun X, Zheng X, Liu Y, Liang H*, Chen S*. The Relationship between Hepatic Myeloid-Derived Suppressor Cells and Clinicopathological Parameters in Patients with Chronic Liver Disease. Biomed Res Int. 2021, 2021:6612477.

  • Jing Xu#, Liangqin Gao, Huiqing Liang, Shaoliang Zhang, Penghua Lai, Shaodong Chen*. Evidence for the anti-NAFLD effectiveness of chlorogenic acid as a HAT inhibitor using in vivo experiments supported by virtual molecular docking. Phytomedicine Plus. 2021, 1(4): 100055.

  • Liang Huiqing#, Liu Yaoyu, Jiang Xiaoqian, Zheng Xiaoting, Tang Jinmo, Yang Jiaen, Zhuang Hongli, Lai Penghua, Peng Li, Guo Zhenying, Cai Shanshan, Luo Dan, Xu Lingxia, Mao Qianguo*, Chen Shaodong*. Impact of Hepatic Steatosis on the Antiviral Effects of PEG-IFN alpha-2a in Patients with Chronic Hepatitis B and the Associated Mechanism. Gastroenterology Research and Practice. 2020, 2020: 1794769.

Grants

  • National Natural Science Foundation of China General Project

    • Based on the regulation of protein ubiquitination mediated TAK1-NF - κ B signaling pathway, to study the mechanism of action of chlorogenic acid geniposide combination therapy for non-alcoholic fatty liver disease, 2022/01-2025/12. (Grants No.: 82174141)

    • The mechanism of action of chlorogenic acid geniposide combination in regulating Kupffer cell polarization therapy for non-alcoholic fatty liver disease based on the gut liver axis, 2017/01-2020/12. (Grants No.: 81673660)

    • Optimization of dosage ratio of chlorogenic acid geniposide combination in the treatment of non-alcoholic fatty liver disease and its mechanism of action on epithelial mesenchymal transition, 2013/01-2016/12. (Grants No.: 81274155)