Curriculum Vitae for XMUM Official Website

BIOGRAPHY

Dr Yeap Swee Keong graduated his PhD from Universiti Putra Malaysia. His research interests including basic and applied immunology, novel food/drug discovery, natural products bioactivities and identification of genetic markers for diseases management and crop improvement. Dr Yeap has received several grants to support his research. In 2019, he was invited as the international expert member for an AHEAD grant funded by World Bank to the Sri Lanka Gov agency. Besides, he was also the Assistant Dean of China-ASEAN College of Marine Sciences and Head of Marine Biotechnology Programme. Currently, he is focusing in the implementation of Outcome Based Education (OBE) to improve the teaching and learning approaches for the Marine Biotechnology Programme.     

RESEARCH INTERESTS

• Animal cell culture (primary culture and cell line)

• Marine microalgae

• Next generation sequencing

• Avian immunology

• Flow cytometry

• Tumor immunology

• Natural product bioactivity

• Drug discovery

EDUCATIONAL BACKGROUND

• PhD (Animal Cell Biotechnology), Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Malaysia (2010)

• BSc (Biotechnology), Universiti Putra Malaysia (2006)

WORKING EXPERIENCE

• Assistant Dean and Professor in China-ASEAN Marine Science School, Xiamen University Malaysia Campus. (Oct 2016 until now)

• Research Fellow in Institute of Biosciences, University Putra Malaysia, Selangor, Malaysia. (Nov 2012-Sept 2016) (Avian Immunology)

• Postdoctoral Researcher in Laboratory of Vaccines and Immunotherapeutics, IBS, UPM, Malaysia (2010-2012) (Avian Immunology)

RESEARCH EXPERIENCE / GRANTS

•   Chemical profiling and in vitro cytotoxicity of local natural extracts. Elkene Sdn Bhd; RM185,955  

•   Acquisition and cultivation of microorganisms for biocontrol and biofertilizer. Kawan Biotech Sdn Bhd; RM75,001.50  

•   Recipient of FRGS 2024 (Ref: FRGS/1/2024/STG01/XMU//1) Elucidating the effect of co-culturing Bacillus amyloliquefaciens and Trichoderma longibrachiatum in improving Okra (Abelmoschus esculentus) growth quality and tolerance against Fusarium oxysporum induced wilt. RM 103,200.00

REPRESENTATIVE PUBLICATIONS

•   Tey, K.Y., Luthfi, A.A.I.,  Manaf, S., Mong, G.R., Woon, K.S., Yeap, S.K., Senan, M.S.,  Jamali, N.S., Tan, J.Pi. 2024. Fibrous oil palm frond as a potential microbial immobilization carrier for enhanced 1,3-propanediol productivity. Journal of Environmental Chemical Engineering, 12 (5).

•   Chong, Z.X., Ho, W.Y., Yeap, S.K. 2024. Decoding the tumour-modulatory roles of LIMK2. Life sciences, 347.  

•   Chong, Z.X., Ho, W.Y., Yeap, S.K. 2024. Tumour-regulatory role of long non-coding RNA HOXA-AS3. Progress in Biophysics and Molecular Biology, 189.

•   Sim, X.Y., Tan, J.P., He, N., Yeap, S.K., Hui, Y.W., Luthfi, A.A.I., Manaf, S.F.A., Bukhari, N.A., Jamali, N.S. 2023.Unraveling the effect of redox potential on dark fermentative hydrogen production. Renewable and Sustainable Energy Reviews,187.

•   Tey, K.Y., Tan, J.P., Yeap, S.K., He, N., Bukhari, N.A., Hui, Y.W., Luthfi, A.A.I., Manaf, S.F.A. 2023. Current analysis on 1,3-propanediol production from glycerol via pure wild strain fermentation. Journal of Environmental Chemical Engineering, 11(5).

•   Chong, Z.X., Yong, C.Y. Ong, A.H., Yeap, S.K., Ho, W.Y. 2023. Deciphering the roles of aryl hydrocarbon receptor (AHR) in regulating carcinogenesis. Toxicology, 495.

•   Aldoghachi, A. F., Chong, Z. X., Yeap, S. K., Cheong, S. K., Ho, W. Y., & Ong, A. H. K. 2023. Stem Cells for Cancer Therapy: Translating the Uncertainties and Possibilities of Stem Cell Properties into Opportunities for Effective Cancer Therapy. International Journal of Molecular Sciences, 24(2), 1012.

•   Ali, N.M., Yeap, S.K., Ho, W.Y., Boo, L., Ky, H., Satharasinghe, D.A., Tan, S.W., Cheong, S.K., Huang, H.D., Lan, K.C., Chiew, M.Y., Ong, H.K. 2021. Adipose MSCs suppress MCF7 and MDA-MB-231 breast cancer metastasis and EMT pathways leading to dormancy via exosomal-miRNAs following co-culture interaction. Pharmaceuticals, 14, 8.

•   Rahim, N.F.C., Hussin, Y., Aziz, M.N.M., Mohamad, N.E., Yeap, S.K., Masarudin, M.J., Abdullah, R., Akhtar, M.N., Alitheen, N.B. 2021. Cytotoxicity and apoptosis effects of curcumin analogue (2E,6E)-2,6-bis(2,3-dimethoxybenzylidine) cyclohexanone (DMCH) on human colon cancer cells HT29 and SW620 in vitro. Molecules, 26, 1261.

•   Yeap, S.K., Ali, N.M., Akhtar, M.N., Razak, N.A., Chong, Z.X., Ho, C.W., Boo, L., Zareen, S., Kurniawan, T.A., Avtar, R., Ng, S.Y.L., Ong, A.H.K., Alitheen, N.B. 2021. Induction of apoptosis and regulation of microRNA expression by (2E,6E)-2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) treatment on MCF-7 breast cancer cells. Molecules, 26, 1277.

•   Chong, Z.X., Yeap, S.K., Ho, W.Y. 2021. Angiogenesis regulation by microRNAs and long none-coding RNAs in human breast cancer. Pathology Research and Practice, 219, 153326.

•   Chong, Z.X., Yeap, S.K., Ho, W.Y. 2021. Dysregulation of miR-638 in the progression of cancers. Pathology Research and Practice, 219, 153326.

•   Aziz, M.N.M., Rahim, N.F.C., Hussin, Y., Yeap, S.K., Masarudin, M.J., Mohamad, N.E., Akhtar, M.N., Osman, M.A., Cheah, Y.K., Noorjahan, B.A. 2021. Anti-metastatic and anti-angiogenic effects of curcumin analog DK1 on human osteosarcoma cells in vitro. Pharmaceuticals, 14, 532.

•   Yeap, S.K., Yong, C.Y., Faruq, U., Ong, H.K., Amin, Z.M., Ho, W.Y., Sharifudin, S., Jaganath, I.B. 2021. In vivo toxicity and antioxidant of pressurize hot water Phyllanthus tenellus Roxb. extracts. BMC Complementary Medicine and Therapies, 21, 86.

•   Yeap, S.K., Ho, W.Y. 2021. Chapter 12: Biological Activities of Non-curcuminoids. In Food Chemistry, Function and Analysis, 249-292.

•   Chong, Z.X., Yeap, S.K., Ho, W.Y. 2021. Role of miRNAs in regulating responses to radiotherapy in human breast cancer. International Journal of Radiation Biology, 97, 289-301.

•   Chong, Z.X., Yeap, S.K., Ho, W.Y. 2021. Regulation of autophagy by microRNAs in human breast cancer. Journal of Biomedical Science, 28, 21.

HONORS/AWARDS

• MAKNA Cancer Award 2013.

Prospective PhD/MSc Applications

• I am not accepting any further PhD/MSc applications.